San Francisco 49ers
- NFC West0-0-0
San Francisco 49ers Schedule
The San Francisco 49ers kick off their 2019 schedule on the road against Tampa Bay on Sunday, Sept. 8.
San Francisco hosts Cleveland on Monday Night Football in Week 5, plays at Arizona on Thursday Night Football in Week 8, and hosts Seattle on Monday night in Week 10.
The 2019 San Francisco 49ers Schedule is listed as the 11th toughest schedule in the NFL. Their opponents in 2019 have a combined record of 129-124-3 (.510) based on last season’s results.