San Francisco 49ers
- NFC West0-0-0
San Francisco 49ers Schedule 2018
The San Francisco 49ers kick off their 2018 schedule on Sunday, Sept. 9 at the Minnesota Vikings.
Featured matchups on the 2018 San Francisco 49ers schedule include a game at Kansas City on Sept. 23, a Monday Night Football matchup at Green Bay on Oct. 15, and Sunday Night Football games at home vs. the Los Angeles Rams on Oct. 21 and at Seattle on Dec. 2.
The 2018 San Francisco 49ers Schedule is tied as the 15th toughest schedule in the NFL. Their opponents in 2018 have a combined record of 128-128 (50.0%) based on last season’s results.