On Monday, ESPN released their 2010 Thursday night college football TV schedule. The season opener on September 2 features a doubleheader with Southern Miss traveling to South Carolina and Hawaii hosting USC.
Listed below is the full television schedule (all times Eastern):
| Date | ACC | Time (ET) |
| Thu, Sep 2 | 7:30 p.m. | Southern Miss at South Carolina |
| Thu, Sep 2 | 11:00 p.m. | USC at Hawaii |
| Thu, Sep 9 | 7:30 p.m. | Auburn at Mississippi State |
| Thu, Sep 16 | 7:30 p.m. | Cincinnati at NC State |
| Thu, Sep 23 | 7:30 p.m. | Miami at Pittsburgh |
| Thu, Sep 30 | 7:30 p.m. | Texas A&M at Oklahoma State |
| Thu, Oct 7 | 7:30 p.m. | Nebraska at Kansas State |
| Thu, Oct 14 | 7:30 p.m. | South Florida at West Virginia |
| Thu, Oct 21 | 9:00 p.m. | UCLA at Oregon |
| Thu, Oct 28 | 7:30 p.m. | Florida State at NC State |
| Thu, Nov 4 | 7:30 p.m. | Georgia Tech at Virginia Tech |
| Thu, Nov 11 | 7:30 p.m. | Pittsburgh at Connecticut |
| Thu, Nov 18 | 8:00 p.m. | UCLA at Washington |
| Thu, Nov 25 | 8:00 p.m. | Texas A&M at Texas |
| Thu, Dec 2 | 8:00 p.m. | Arizona State at Arizona |