Other top games include (15) Kansas State at (6) Oklahoma, Missouri at (7) South Carolina, Maryland at (8) West Virginia, and (18) Michigan at (11) Notre Dame.
ESPN Gameday will broadcast live from Tallahassee, Florida, the site of a top ten ACC match-up between 4th ranked Florida State and 10th ranked Clemson.
A #MACtion game between Kent State and Buffalo kicks off the schedule on Wednesday night at 7 p.m. ET on ESPNU.
Listed below are the games with TV, time and network. The schedule is also optimized for printing:
| Wednesday, Sept. 19, 2012 | |||
| Game | Time (ET) | Network | Online |
| Kent State at Buffalo | 7:00 p.m. | ESPNU (HD) | ESPN3 |
| Thursday, Sept. 20, 2012 | |||
| BYU at Boise State | 9:00 p.m. | ESPN (HD) | — |
| Friday, Sept. 21, 2012 | |||
| Baylor at Louisiana Monroe | 8:00 p.m. | ESPN (HD) | ESPN3 |
| Saturday, Sept. 22, 2012 | |||
| Bowling Green at Virginia Tech | 12:00 p.m. | ESPNU (HD) | ESPN3 |
| Central Michigan at Iowa | 12:00 p.m. | BTN (HD) | btn2go |
| Maryland at West Virginia | 12:00 p.m. | FX (HD) | — |
| Ole Miss at Tulane | 12:00 p.m. | FSN (HD)/FCSC | — |
| UMass at Miami (OH) | 12:00 p.m. | ERTV/ESPN-GP | ESPN3 |
| UAB at Ohio State | 12:00 p.m. | BTN (HD) | btn2go |
| UTEP at Wisconsin | 12:00 p.m. | ESPN2 (HD) | ESPN3 |
| Virginia at TCU | 12:00 p.m. | ESPN (HD) (3D) | ESPN3 |
| Kentucky at Florida | 12:21 p.m. | SEC Network (HD)/ESPN-GP | ESPN3 |
| Army at Wake Forest | 12:30 p.m. | ACC Network (HD)/ESPN-GP | ESPN3 |
| UConn at Western Michigan | 2:00 p.m. | — | ESPN3 |
| Norfolk State at Ohio | 2:00 p.m. | — | ESPN3 |
| Miami at Georgia Tech | 3:00 p.m. | FSN (HD)/ESPN-GP | ESPN3 |
| East Carolina at North Carolina | 3:30 p.m. | ESPNU (HD) | — |
| Eastern Michigan at Michigan St. | 3:30 p.m. | BTN (HD) | btn2go |
| Idaho State at Nebraska | 3:30 p.m. | BTN (HD) | btn2go |
| Marshall at Rice | 3:30 p.m. | CSBA/CSS | — |
| Missouri at South Carolina | 3:30 p.m. | CBS (HD) | CBSSports |
| Oregon State at UCLA | 3:30 p.m. | ABC or ESPN2 (HD) | — |
| South Dakota at Northwestern | 3:30 p.m. | BTN (HD) | btn2go |
| Temple at Penn State | 3:30 p.m. | ABC or ESPN2 (HD) | — |
| VMI at Navy | 3:30 p.m. | CBSSN (HD) | — |
| Gardner Webb at Pittsburgh | 3:30 p.m. | — | ESPN3 |
| Kansas at Northern Illinois | 3:30 p.m. | — | ESPN3 |
| Colorado at Washington State | 4:00 p.m. | FX (HD) | — |
| South Florida at Ball State | 4:30 p.m. | SNY/MASN/ERTVESPN-GP | ESPN3 |
| Florida Atlantic at Alabama | 5:00 p.m. | PPV (AL,FL)/ESPN-GP | — |
| Wyoming at Idaho | 5:00 p.m. | — | ESPN3 |
| California at USC | 6:00 p.m. | Pac-12 Network (HD) | Pac-12 |
| The Citadel at NC State | 6:00 p.m. | — | ESPN3 |
| Memphis at Duke | 6:00 p.m. | — | ESPN3 |
| LSU at Auburn | 7:00 p.m. | ESPN (HD) | — |
| Rutgers at Arkansas | 7:00 p.m. | ESPNU (HD) | — |
| South Alabama at Mississippi St. | 7:00 p.m. | PPV (MS)/ESPN-GP | ESPN3 |
| South Carolina St. at Texas A&M | 7:00 p.m. | FS South (HD)/ESPN-GP | — |
| Alcorn State at Arkansas State | 7:00 p.m. | — | ESPN3 |
| Coastal Carolina at Toledo | 7:00 p.m. | — | ESPN3 |
| Louisville at FIU | 7:00 p.m. | — | ESPN3 |
| Southern Miss at W. Kentucky | 7:00 p.m. | — | ESPN3 |
| Stephen F. Austin at Texas State | 7:00 p.m. | — | Video |
| Troy at North Texas | 7:00 p.m. | — | ESPN3 |
| Utah State at Colorado State | 7:00 p.m. | KTVD | Video |
| Akron at Tennessee | 7:30 p.m. | CSS/CST/ESPN-GP | ESPN3 |
| Michigan at Notre Dame | 7:30 p.m. | NBC (HD) | — |
| Vanderbilt at Georgia | 7:45 p.m. | ESPN2 (HD) | — |
| Kansas State at Oklahoma | 7:50 p.m. | FOX (HD) | — |
| Clemson at Florida State | 8:00 p.m. | ABC (HD) | — |
| Fresno State at Tulsa | 8:00 p.m. | CBSSN (HD) | — |
| Louisiana Tech at Illinois | 8:00 p.m. | BTN (HD) | btn2go |
| Syracuse at Minnesota | 8:00 p.m. | BTN (HD) | btn2go |
| New Mexico at New Mexico St. | 8:00 p.m. | — | ESPN3 |
| San Jose St. at San Diego St. | 8:00 p.m. | KUSI TV | — |
| Air Force at UNLV | 10:00 p.m. | ALT | — |
| Utah at Arizona State | 10:00 p.m. | Pac-12 Network (HD) | Pac-12 |
| Nevada at Hawaii | 10:30 p.m. | NBCSN (HD) | — |
| Arizona at Oregon | 10:30 p.m. | ESPN (HD) | — |